Single-pot granulation has been used in the pharmaceutical industry for decades. Single-pot granulation combines the mixing, high-shear wet granulation and drying (vacuum drying, carrier-gas drying, or microwave drying) all in one process bowl.
L.B. Bohle’s single-pot granulation portfolio includes R&D systems for small production volumes as well as production-scale systems.
The VMA product range includes classic single-pot granulators with agitator and chopper units and a top drive. Two stirrers produce the shearing action and loosen the product. This helps to prevent clumping and ensures that the resulting granule is of optimum quality. The GMP-compliant process bowl with a double shell is the core of the VMA.
The main aggregates are integrated into the lid of the granulation pot (top drive).
The process bowl is emptied through a cone-shaped sieve (BTS 200) via the floor outlet into a container (IBC). Recipe-controlled cleaning is carried out automatically. The VMA produces batch sizes from 20 to 960 litres and can be installed in explosive atmospheres.
|Safe production inside a closed bowl in a vacuum|
|High mixing and granulation efficiency (even for low doses of active agents at < 1%)|
|Low energy consumption: Drying at low temperatures|
|Easy operation and cleaning, as well as quick product changes|
|Efficient solvent recovery through cooling water|
Our product brochure for granulation with the Single-Pot Granulator is available for download here:
We offer our Single-Pot Granulator in different sizes and technical designs.
Our product brochure for granulation with the Single-Pot Granulator is available for download here.
The following list provides an initial overview and comparison of our various Single-Pot Granulators for your granulation.
We look forward to your request for detailed information.
|VMA 70||VMA 300||VMA 600||VMA 1200|
|Dimensions (LxWxH) mm||1800 x 1300 x 2500||2290 x 1650 x 2950||2525 x 1850 x 3350||3365 x 2150 x 4400|
|Control system||PLC, In Touch visualisation by Wonderware||PLC, In Touch visualisation by Wonderware||PLC, In Touch visualisation by Wonderware||PLC, In Touch visualisation by Wonderware|