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Single-Pot Granulator for the Pharmaceutical Industry

Single-Pot Granulation – VMA

Single-pot granulation has been used in the pharmaceutical industry for decades. Single-pot granulation combines the mixing, high-shear wet granulation and drying (vacuum drying, carrier-gas drying, or microwave drying) all in one process bowl.

L.B. Bohle’s single-pot granulation portfolio includes R&D systems for small production volumes as well as production-scale systems.

Single-Pot Granulation VMA 600


Granulation with the L.B. Bohle
Single-Pot Granulator

The VMA product range includes classic single-pot granulators with agitator and chopper units and a top drive. Two stirrers produce the shearing action and loosen the product. This helps to prevent clumping and ensures that the resulting granule is of optimum quality. The GMP-compliant process bowl with a double shell is the core of the VMA.

The main aggregates are integrated into the lid of the granulation pot (top drive).

The process bowl is emptied through a cone-shaped sieve (BTS 200) via the floor outlet into a container (IBC). Recipe-controlled cleaning is carried out automatically. The VMA produces batch sizes from 20 to 960 litres and can be installed in explosive atmospheres.




Benefits of the
Single Pot Granulator

Safe production inside a closed bowl in a vacuum
High mixing and granulation efficiency (even for low doses of active agents at < 1%)
Low energy consumption: Drying at low temperatures
Easy operation and cleaning, as well as quick product changes
Efficient solvent recovery through cooling water
Small footprint

Our product brochure for granulation with the Single-Pot Granulator is available for download here:

Show Product brochure

Technische Merkmale

Variations and
Technical Features

We offer our Single-Pot Granulator in different sizes and technical designs.

Our product brochure for granulation with the Single-Pot Granulator is available for download here:

Show Product brochure

The following list provides an initial overview and comparison of our various Single-Pot Granulators for your granulation.

We look forward to your request for detailed information.

VMA 70 VMA 300 VMA 600 VMA 1200
Dimensions (LxWxH) mm 1800 x 1300 x 2500 2290 x 1650 x 2950 2525 x 1850 x 3350 3365 x 2150 x 4400
Control system PLC, In Touch visualisation by Wonderware PLC, In Touch visualisation by Wonderware PLC, In Touch visualisation by Wonderware PLC, In Touch visualisation by Wonderware



L.B. Bohle: Leader in Pharma Granulation Technology

L.B. Bohle provides top-of-the-line granulation solutions such as the VMA single-pot granulator, BFS fluid bed systems, and BRC roller compactors. These technologies offer efficient, safe, and environmentally friendly production processes, perfect for the manufacture of solid dosage forms in the pharmaceutical industry.
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Your contact for the
Single Pot Granulator

Ingo Küsel

Area Sales Manager
+49 2524 – 93 23 0

Ingo Küsel, L.B. Bohle


Potential subjects of interest

Maschines and Processes by L.B. Bohle

Machines & Processes

Product efficiency increase is the central benefit of L.B. Bohle. To this end, we offer both complete production plants and solutions for individual production steps.

Our product portfolio

L.B. Bohle: Free Whitepaper and Product brochures

Free Whitepaper & Product brochures

Learn more about our innovative machine technologies and processes and convince yourself of the advantages for pharmaceutical production with the help of our white papers and product brochures.

Register now!


We look forward to hearing from you!

+49 (0) 25 24 93 23-0

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