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Continuous granulation and drying for the pharmaceutical industry

QbCon® 1 - R&D

All developments start in a lab. Continuous processes also require lab-size equipment with small footprints that can handle even very small throughputs.
Continuous wet granulation and drying have been subject to discussion for some time in pharmaceutical research and development (R&D) of oral pharmaceutical solids.

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Continuous granulation and drying with QbCon® 1 by L.B. Bohle

Granulation and granule drying also play a major role in continuous manufacturing. QbCon® 1 is the only system for research and development world-wide that meets the quality demands of pharmaceutical manufacture.

First of all, a short residence time of the granules in the dryer with a narrow residence time distribution is essential to be able to remove defective products in a targeted manner without having to discard a large portion of the batch.

Furthermore, narrow residence time distributions simplify the traceability of material in the continuous process, making it easier and less complex to trace finished tablets back to the basic products or to subsequently trace them from the basic products to the finished tablet.

Further important quality requirements for a dryer are

  1. Even, reproducible drying of all granules – especially of different
    sizes – over the entire process duration
  2. A small process chamber to keep the volume in the drying process as low as possible
  3. And, in particular, a long service life of the exhaust air filters without having to interrupt the drying process or even replace

Thanks to the small footprint, the QbCon® 1 is perfect for the smallest throughputs (nominal throughput: 0.5–2.5 kg/h).

Vorteile

Benefits of the continuous
wet granulator and dryer

Fully automatic cleaning of the filter during the drying process
Gentle, uniform drying through gentle fluidization and transport
Uniform conveying of the granules from charging to discharge
Comfortable handling and easy cleaning
Very short residence time of granules of different sizes
Fast development of new products – secured scale-up

Our product brochure for the continuous wet granulator and dryer for research and development is available for download here:

Show Product brochure

Technische Merkmale

Variation and
Technical Features

The following list provides an initial overview for our research and development system.
We look forward to your request for detailed information.

DimensionsApprox. 2070 x 920 x 1848 mm
Weight750 kg
Nominal throughput0,5 – 2,5 kg

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Ansprechpartner

Your contact for the
Continuous Wet Granulators and Dryers

Burkhard Schmidt

Sales Director
inquiry@lbbohle.de
+49 2524 – 93 23 0

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Potential subjects of interest

Continuous_Drying_BCD_570x286

Continuous drying

Constant and continuous drying must be ensured in order to seamlessly connect to continuous wet granulation. With the continuous BCD fluidized bed dryer, L.B. Bohle enables continuous drying of granules for the first time.

Learn more about Continuous Drying

Trockengranulierer / Roller Compactor BRC

BRC Dry Granulator

L.B. Bohle meets the rising market demands for continuous processes with the BRC 25 and the BRC 100,an innovative dry granulator with gap control. The BRC series combines high product capacity with minimal material loss.

Go to our Dry Granulators

Contact

We look forward to hearing from you!

+49 (0) 25 24 93 23-0
info@lbbohle.com

Go to the contact page

Contact

We look forward to hearing from you!

+49 (0) 25 24 93 23-0
info@lbbohle.com

Go to the contact page