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Fluidized Bed System for the Pharmaceutical Industry

Fluidized Bed Granulator & Fluidized Bed Dryer BFS

Fluidized bed systems have been used in the pharmaceutical industry for many decades. Adding an aqueous or alcoholic granulation medium compresses the mixture of dry powder particles. The fluid contains a volatile solvent which can be removed by drying. For a long time, fluidized bed solutions were dominated by top-spray. However, the benefits of systems with tangential spray nozzles have become more apparent, thus tending to take over top-spray granulators. L.B. Bohle’s fluid bed granulation portfolio includes R&D systems for small production volumes as well as production scale systems.



Granulation with the
Bohle Fluid Bed Granulator

L.B. Bohle uses the Bohle Uni Cone BUC® process to optimize fluidized bed

The patented Bohle Uni Cone BUC® is a specially slotted air distributor plate with a conical displacement cone. This design allows for a complete fluidization of the particles. This tangential particle motion achieves a uniform film, e.g. on pellets, without any twins.

Since the fluidized particles or granules move tangentially at relatively low fluidization height, they do not require a high-volume expansion. This reduces the required installation height, saving costs and production floor space.

At least six filter elements of the BFS, that can be cleaned separately, ensure that the air flow though the product bed is uninterrupted.

Drying, granulation and coating without need for alteration

Another advantage of the tangential design in facilities from L.B. Bohle is that granulation, coating and drying can be carried out in a single system without having to reconfigure the equipment.

For the drying process, the BFS fluidized bed system can be equipped with an online moisture measurement system using NIR technology (similar to infra-red analysis). This innovation makes it possible to identify the current moisture level, precisely and reproducibly, during the granulation and drying process.


Comparison of Fluidized Bed Equipment

Graphic_Tangential Fluid Bed
Wurster Process

Benefits Bohle Uni Cone BUC®

BUC Tangential Spray
Effective air distribution:
Quite narrow particle size distribution and formation of spherical granules
Frameless product bottom plate design:
Simple cleaning
Inspection of air plenum through the back pipe:
Avoidance of cross contamination in the bowl inlet
Filter inspection:
Safe location for the operator standing on the floor
Handling of the bottom plate:
Safe de-installation in combination with an in-wall built lifting column




Benefits of the Fluid Bed Granulator

Complete fluidization of particles
Even film coating, no twin formation
Integration of PAT, NIR and WIP
Patented filter cleaning – patented diffuser
Lowering of filters via electric drive
Easy-to-remove distributor plate
Low installation height, efficient space utilization
Pressure surge resistance up to 12 bar- optimum conditions for containment applications

Our product brochure for granulation with the fluidized bed system is available for download here:

Show Product brochure

Technische Merkmale

Variations and
Technical Features

We offer our fluidized bed systems in different sizes and technical designs.

The following list provides an initial overview and comparison of our various fluidized bed systems for your granulation. Our product brochure for granulation with the fluidized bed system is available for download here:

Show Product brochure

We look forward to your request for detailed information.

BFS series Qty. of product filter bags Height of the fluidized bed system [mm] Number of nozzles (tangential spray) Control system
BFS 30 4 ca. 1980 1 PLC controlled, Touchpanel operated
BFS 60 6 ca. 2930 2 PLC controlled, Touchpanel operated
BFS 120 6 ca. 3600 3 PLC controlled, Touchpanel operated
BFS 240 9 ca. 3920 4 PLC controlled, Touchpanel operated
BFS 360 12 ca. 4570 5 PLC controlled, Touchpanel operated
BFS 480 10 ca. 4990 6 PLC controlled, Touchpanel operated



Whitepaper on
Fluid Bed Granulation
and Drying BFS

Bohle Fluid Bed System –
Multipurpose Equipment for Drying,
Granulation and Coating.

Download now


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Your contact for the Bohle
Fluid Bed Granulator

Joschka Raby

Area Sales Manager
+49 2524 – 93 23 0

Joschka Raby


Potential subjects of interest

Maschines and Processes by L.B. Bohle

Machines & Processes

Product efficiency increase is the central benefit of L.B. Bohle. To this end, we offer both complete production plants and solutions for individual production steps.

Our product portfolio

L.B. Bohle: Free Whitepaper and Product brochures

Free Whitepaper & Product brochures

Learn more about our innovative machine technologies and processes and convince yourself of the advantages for pharmaceutical production with the help of our white papers and product brochures.

Register now!


We look forward to hearing from you!

+49 (0) 25 24 93 23-0

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