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Fluidized Bed System for the Pharmaceutical Industry

Fluidized Bed Granulator & Fluidized Bed Dryer BFS

Fluidized bed systems have been used in the pharmaceutical industry for many decades. Adding an aqueous or alcoholic granulation medium compresses the mixture of dry powder particles. The fluid contains a volatile solvent which can be removed by drying. For a long time, fluidized bed solutions were dominated by top-spray. However, the benefits of systems with tangential spray nozzles have become more apparent, thus tending to take over top-spray granulators. L.B. Bohle’s fluid bed granulation portfolio includes R&D systems for small production volumes as well as production scale systems.

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Granulation with the
Bohle Fluid Bed Granulator

L.B. Bohle uses the Bohle Uni Cone BUC® process to optimize fluidized bed

The patented Bohle Uni Cone BUC® is a specially slotted air distributor plate with a conical displacement cone. This design allows for a complete fluidization of the particles. This tangential particle motion achieves a uniform film, e.g. on pellets, without any twins.

Since the fluidized particles or granules move tangentially at relatively low fluidization height, they do not require a high-volume expansion. This reduces the required installation height, saving costs and production floor space.

At least six filter elements of the BFS, that can be cleaned separately, ensure that the air flow though the product bed is uninterrupted.

Drying, granulation and coating without need for alteration

Another advantage of the tangential design in facilities from L.B. Bohle is that granulation, coating and drying can be carried out in a single system without having to reconfigure the equipment.

For the drying process, the BFS fluidized bed system can be equipped with an online moisture measurement system using NIR technology (similar to infra-red analysis). This innovation makes it possible to identify the current moisture level, precisely and reproducibly, during the granulation and drying process.

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Vorteile

Benefits of the Fluid Bed Granulator

Complete fluidization of particles
Even film coating, no twin formation
Integration of PAT, NIR and WIP
Patented filter cleaning – patented diffuser
Lowering of filters via electric drive
Easy-to-remove distributor plate
Low installation height, efficient space utilization
Pressure surge resistance up to 12 bar- optimum conditions for containment applications

Our product brochure for granulation with the fluidized bed system is available for download here:

Show Product brochure

Technische Merkmale

Variations and
Technical Features

We offer our fluidized bed systems in different sizes and technical designs.

The following list provides an initial overview and comparison of our various fluidized bed systems for your granulation. Our product brochure for granulation with the fluidized bed system is available for download here.

We look forward to your request for detailed information.

BFS seriesQty. of product filter bagsHeight of the fluidized bed system [mm]Number of nozzles (tangential spray)Control system
BFS 304ca. 19801PLC controlled, Touchpanel operated
BFS 606ca. 29302PLC controlled, Touchpanel operated
BFS 1206ca. 36003PLC controlled, Touchpanel operated
BFS 2409ca. 39204PLC controlled, Touchpanel operated
BFS 36012ca. 45705PLC controlled, Touchpanel operated
BFS 48010ca. 49906PLC controlled, Touchpanel operated

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Ansprechpartner

Your contact for the Bohle
Fluid Bed Granulator

Joachim Kraft

Area Sales Manager
inquiry@lbbohle.de
+49 2524 – 93 23 0

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Other granulation methods

Eintopfgranulierer_VMA

Single-Pot Granulation

The VMA Single Pot Granulator is a granulating system specifically optimized for pharmaceutical applications. The three process steps of blending, high-shear-wet granulation and drying are implemented in a closed process bowl.
The VMA produces batch sizes from 20 to 960 liters.

More about the Single-Pot Granulator

Compact_unit

Compact Granulation System

Small footprint, high quality: The compact unit is an effective solution when traditional wet granulation must be economical and ergonomically sound. Process, cleaning, control, explosion protection and zone concept as well as qualification are closely coordinated.

Go to the Granulation System

Contact

We look forward to hearing from you!

+49 (0) 25 24 93 23-0
info@lbbohle.com

Go to the contact page

Contact

We look forward to hearing from you!

+49 (0) 25 24 93 23-0
info@lbbohle.com

Go to the contact page